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human ctla 4  (R&D Systems)


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    Structured Review

    R&D Systems human ctla 4
    Human Ctla 4, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 8 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/recombinant+mouse+ctla/Recombinant+Mouse+CTLA-4+Fc+Chimera+Protein/us12503510-895-56-58
    Average 93 stars, based on 8 article reviews
    human ctla 4 - by Bioz Stars, 2026-09
    93/100 stars

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    Related Articles

    Enzyme-linked Immunosorbent Assay:

    Article Title: Local secretion of anti-CTLA-4 enhances the therapeutic efficacy of a cancer immunotherapy with reduced evidence of systemic autoimmunity.
    Article Snippet: The antibody expressing cells were used as a population derived from a single round of infection, and expression of the anti-CTLA-4 protein was conWrmed using IgG2b (Bethyl) and anti-CTLA-4 speciWc ELISAs. .. The latter ELISA was performed using plates coated with recombinant mouse CTLA-4/Fc chimeric protein (R&D systems). .. Mice BALB/c and C57BL/6 mice were purchased from Taconic and DO11.10 mice were purchased from The Jackson Laboratory.

    Article Title: Local secretion of anti-CTLA-4 enhances the therapeutic efficacy of a cancer immunotherapy with reduced evidence of systemic autoimmunity
    Article Snippet: The antibody expressing cells were used as a population derived from a single round of infection, and expression of the anti-CTLA-4 protein was confirmed using IgG2b (Bethyl) and anti-CTLA-4 specific ELISAs. .. The latter ELISA was performed using plates coated with recombinant mouse CTLA-4/Fc chimeric protein (R&D systems). .. Mice BALB/c and C57BL/6 mice were purchased from Taconic and DO11.10 mice were purchased from The Jackson Laboratory.

    Recombinant:

    Article Title: Local secretion of anti-CTLA-4 enhances the therapeutic efficacy of a cancer immunotherapy with reduced evidence of systemic autoimmunity.
    Article Snippet: The antibody expressing cells were used as a population derived from a single round of infection, and expression of the anti-CTLA-4 protein was conWrmed using IgG2b (Bethyl) and anti-CTLA-4 speciWc ELISAs. .. The latter ELISA was performed using plates coated with recombinant mouse CTLA-4/Fc chimeric protein (R&D systems). .. Mice BALB/c and C57BL/6 mice were purchased from Taconic and DO11.10 mice were purchased from The Jackson Laboratory.

    Article Title: CD80 and CD86 C domains play an important role in receptor binding and co-stimulatory properties.
    Article Snippet: Paired antibodies and required cytokine standards for detecting mouse IL-2 and IFN-g (BD PharMingen) were used in ELISA. .. Recombinant mouse CTLA-4±Ig (rmCTLA-4±Ig) was purchased from R & D Systems and used in the binding assay. ..

    Article Title: Intercellular exchange of class II major histocompatibility complex/peptide complexes is a conserved process that requires activation of T cells but is constitutive in other types of antigen presenting cell.
    Article Snippet: Activated T cells acquire antigen presenting cell(APC) derived class II major histocompatibility complex glycoproteins (MHCII) but the role of TCR in this process is controversial.. This study provides additional evidence that ligation of TCR initiates activation-dependent processes that independently mediate acquisition of APC-derived molecules.. First, intercellular exchange of MHCII resulted in the constitutive accumulation of xenogeneic rat I-A on murine B cells, whereas naı̈ve murine T cells required activation to adsorb xenogeneic I-A.

    Article Title: Marginal zone, but not follicular B cells, are potent activators of naive CD4 T cells.
    Article Snippet: .. B cells obtained from mice primed with Ag 8 h previously were irradiated and preincubated at 4°C with 2.5 g/ml blocking reagents, antiB7.1, anti-B7.2, a combination of anti-B7.1 and B7.2 mAbs (BD PharMingen, San Diego, CA), or recombinant mouse CTLA-4/Fc chimera (R&D Systems, Minneapolis, MN). ..

    Binding Assay:

    Article Title: CD80 and CD86 C domains play an important role in receptor binding and co-stimulatory properties.
    Article Snippet: Paired antibodies and required cytokine standards for detecting mouse IL-2 and IFN-g (BD PharMingen) were used in ELISA. .. Recombinant mouse CTLA-4±Ig (rmCTLA-4±Ig) was purchased from R & D Systems and used in the binding assay. ..

    Irradiation:

    Article Title: Marginal zone, but not follicular B cells, are potent activators of naive CD4 T cells.
    Article Snippet: .. B cells obtained from mice primed with Ag 8 h previously were irradiated and preincubated at 4°C with 2.5 g/ml blocking reagents, antiB7.1, anti-B7.2, a combination of anti-B7.1 and B7.2 mAbs (BD PharMingen, San Diego, CA), or recombinant mouse CTLA-4/Fc chimera (R&D Systems, Minneapolis, MN). ..

    Blocking Assay:

    Article Title: Marginal zone, but not follicular B cells, are potent activators of naive CD4 T cells.
    Article Snippet: .. B cells obtained from mice primed with Ag 8 h previously were irradiated and preincubated at 4°C with 2.5 g/ml blocking reagents, antiB7.1, anti-B7.2, a combination of anti-B7.1 and B7.2 mAbs (BD PharMingen, San Diego, CA), or recombinant mouse CTLA-4/Fc chimera (R&D Systems, Minneapolis, MN). ..



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